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Effect of mitomycin on normal dermal fibroblast and HaCat cell: an in vitro study

1 Dec 2012

Abstract excerpt

OBJECTIVE: To evaluate the effects of mitomycin on the growth of human dermal fibroblast and immortalized human keratinocyte line (HaCat cell), particularly the effect of mitomycin on intracellular messenger RNA (mRNA) synthesis of collagen and growth factors of fibroblast. METHODS: The normal dermal fibroblast and HaCat cell were cultured in vitro. Cell cultures were exposed to 0.4 and 0.04 mg/ml of mitomycin...

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PMID: 23225855
DOI: 10.1631/jzus.b1200055

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