Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole-genome detection of disease-associated deletions or excess homozygosity in a case-control study of rheumatoid arthritis.

Human molecular genetics - 15 Mar 2013

Wu Chih-Chieh, Shete Sanjay, Jo Eun-Ji, Xu Yaji, Lu Emily Y, Chen Wei V, Amos Christopher I

Abstract excerpt

Unlike genome-wide association studies, few comprehensive studies of copy number variation's contribution to complex human disease susceptibility have been performed. Copy number variations are abundant in humans and represent one of the least well-studied classes of genetic variants; in addition, known rheumatoid arthritis susceptibility loci explain only a portion of familial clustering. Therefore, we performed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Genome-Wide Association Study

Share to Homozygote

Share to Polymorphism, Single Nucleotide

Share to Sequence Deletion

Source

Open in PubMed Open full text

Identifiers

PMID: 23223014
DOI: 10.1093/hmg/dds512
PMCID: PMC3578409

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole-genome detection of disease-associated deletions or excess homozygosity in a case-control study of rheumatoid arthritis.PMID 23223014Read ↗

Detection of disease-associated deletions in case-control studies using SNP genotypes with application to rheumatoid arthritis.Semantic proximity Read ↗

Copy number variation in the human genome and its implication in autoimmunity.Semantic proximity Read ↗

Whole genome association study of rheumatoid arthritis using 27 039 microsatellites.Semantic proximity Read ↗

Autosome-wide copy number variation association analysis for rheumatoid arthritis using the WTCCC high-density SNP genotype data.Semantic proximity Read ↗

Genome‐Wide Copy Number Variation Analysis Identifies Deletion Variants Associated With Ankylosing SpondylitisSemantic proximity Read ↗

A genome-wide screen of gene-gene interactions for rheumatoid arthritis susceptibility.Semantic proximity Read ↗

A simple and efficient algorithm for genome-wide homozygosity analysis in disease.Semantic proximity Read ↗

Hotspots of large rare deletions in the human genome.Semantic proximity Read ↗

Understanding the Genomic Structure of Copy-Number Variation of the Low-Affinity Fcγ Receptor Region Allows Confirmation of the Association of FCGR3B Deletion with Rheumatoid Arthritis.Semantic proximity Read ↗

A 129-kb deletion on chromosome 12 confers substantial protection against rheumatoid arthritis, implicating the gene SLC2A3.Semantic proximity Read ↗

Genetic variation in human disease and a new role for copy number variants.Semantic proximity Read ↗

Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.