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Genetics and iron in the systems biology of Parkinson’s disease and some related disorders

7 Dec 2012

Abstract excerpt

The systems biology approach to complex diseases recognises that a potentially large number of biochemical network elements may be involved in disease progression, especially where positive feedback loops can be identified. Most of these network elements will be encoded by genes, for which different alleles may affect the network(s) differentially. A primary requirement is therefore to determine the relevant...

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PMID: 23220386
DOI: 10.1016/j.neuint.2012.11.015

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