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Random forests-based differential analysis of gene sets for gene expression data.

Gene - 10 Apr 2013

Hsueh Huey-Miin, Zhou Da-Wei, Tsai Chen-An

Abstract excerpt

In DNA microarray studies, gene-set analysis (GSA) has become the focus of gene expression data analysis. GSA utilizes the gene expression profiles of functionally related gene sets in Gene Ontology (GO) categories or priori-defined biological classes to assess the significance of gene sets associated with clinical outcomes or phenotypes. Many statistical approaches have been proposed to determine whether such...

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PMID: 23219997
DOI: 10.1016/j.gene.2012.11.034

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