Article
Extragenetic factors and clinical penetrance of DYT1 dystonia: an exploratory study.
Journal of neurology - 1 Apr 2013
Martino D, Gajos A, Gallo V, Cif L, Coubes P, Tinazzi M, Schneider S A, Fiorio M, Zorzi G, Nardocci N, Ben-Shlomo Y, Edwards M J, Bhatia K P
Abstract excerpt
Factors modifying the clinical penetrance of DYT1 dystonia are incompletely defined. Particularly, the contribution of extragenetic factors has been subject to only limited investigation and remains largely unexplored. A possible effect of childhood infections has been proposed, and the effect of other factors, such as perinatal adversity and trauma, has not been systematically investigated. We performed an...
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