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Article

Chitinase Dependent Control of Protozoan Cyst Burden in the Brain

29 Nov 2012

Abstract excerpt

Chronic infections represent a continuous battle between the host's immune system and pathogen replication. Many protozoan parasites have evolved a cyst lifecycle stage that provides it with increased protection from environmental degradation as well as endogenous host mechanisms of attack. In the case of Toxoplasma gondii, these cysts are predominantly found in the immune protected brain making clearance of the...

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PMID: 23209401
DOI: 10.1371/journal.ppat.1002990

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