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Article

Regulation of Early Adipose Commitment by Zfp521

27 Nov 2012

Abstract excerpt

While there has been significant progress in determining the transcriptional cascade involved in terminal adipocyte differentiation, less is known about early events leading to lineage commitment and cell fate choice. It has been recently discovered that zinc finger protein 423 (Zfp423) is an early actor in adipose determination. Here, we show that a close paralog of Zfp423, Zfp521, acts as a key regulator of...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 23209378
DOI: 10.1371/journal.pbio.1001433

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