Article
Genetically modified VSV(NJ) vector is capable of accommodating a large foreign gene insert and allows high level gene expression.
Virus research - 1 Jan 2013
An Hwa-Yong, Kim Gyoung Nyoun, Wu Kunyu, Kang C Yong
Abstract excerpt
It is desirable to develop a RNA virus vector capable of accommodating large foreign genes for high level gene expression. Vesicular stomatitis virus (VSV) has been used as a gene expression vector, especially Indiana serotype (VSV(Ind)), but less with New Jersey serotype (VSV(NJ)). Here, we report constructions of genetically modified rVSV(NJ) vector carrying various lengths of human hepatitis C virus (HCV)...
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