Article
Genome, epigenome and transcriptome analyses of a pair of monozygotic twins discordant for systemic lupus erythematosus.
Human immunology - 1 Feb 2013
Furukawa Hiroshi, Oka Shomi, Matsui Toshihiro, Hashimoto Atsushi, Arinuma Yoshiyuki, Komiya Akiko, Fukui Naoshi, Tsuchiya Naoyuki, Tohma Shigeto
Abstract excerpt
Information to distinguish genetic and environmental factors in the pathogenesis of multifactorial diseases can be obtained by investigation of disease development in monozygotic twins. Recent reports have shown that there are genomic and epigenomic differences between monozygotic twins. Genomic/epigenomic and gene expression analyses were performed in monozygotic twins discordant for systemic lupus erythematosus...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
