[Mucoviscidosis: CFTR mutation-specific therapy: a ray of sunshine in a cloudy sky].

Abstract excerpt

There is a need to find a cure for pulmonary disease in cystic fibrosis (CF), though full benefit of this approach will be restricted to those patients with well-preserved lungs. The most promising route is currently that of a pharmacological mutation-specific approach aiming at correcting the mechanism by which mutations lead to impairment of chloride conductance across respiratory epithelial cells. In the past...

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