Article
Expression strategy of a phlebovirus: biogenesis of proteins from the Rift Valley fever virus M segment.
Journal of virology - 1 Apr 1990
Suzich J A, Kakach L T, Collett M S
Abstract excerpt
The middle (M) RNA segment of Rift Valley fever virus (RVFV) encodes four proteins: the major viral glycoproteins G2 and G1, a 14-kilodalton (kDa) protein, and a 78-kDa protein. These proteins are derived from a single large open reading frame (ORF) present in the virus-complementary M-segment mRNA. We used recombinant vaccinia viruses in which sequences representing the M-segment ORF were engineered as a...
Topics
- Base Sequence
- Bunyaviridae
- Cloning, Molecular
- Codon
- Genetic Vectors
- Glycoproteins
- Molecular Sequence Data
- Molecular Weight
- Mutation
- Protein Biosynthesis
- RNA, Viral
- Radioimmunoprecipitation Assay
