Article
The host genotype influences infectious bursal disease virus pathogenesis in chickens by modulation of T cells responses and cytokine gene expression.
Developmental and comparative immunology - 1 May 2013
Tippenhauer Merve, Heller Dan E, Weigend Steffen, Rautenschlein Silke
Abstract excerpt
The immunopathogenesis of infectious bursal disease virus (IBDV) was investigated in different layer and broiler type chickens in comparison to highly susceptible specific-pathogen-free layers (SPF-Wh-LT) often used for experimental studies. Layer-type chickens (LT) of all genetic backgrounds showed significantly higher IBDV antigen loads in the bursa of Fabricius (BF) compared to broiler type birds (BT)...
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