Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression analysis of inflammasomes in experimental models of inflammatory and fibrotic liver disease

28 Nov 2012

Abstract excerpt

During inflammation, the inflammasomes representing a group of multi-protein complexes trigger the biological maturation of pro-inflammatory cytokines such as interleukin-1β and interleukin-18 by proteolytic activation of caspase-1 from its inactive proforms. The individual genes encoding components of the inflammasome machinery are regulated at transcriptional and post-transcriptional levels. Once activated,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Inflammasome and immune disorders
Share to Liver Disease Diagnosis and Treatment
Share to Macrophage Migration Inhibitory Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23192004
DOI: 10.1186/1476-9255-9-49

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression analysis of inflammasomes in experimental models of inflammatory and fibrotic liver diseasePMID 23192004Read ↗

NLRP3 Inflammasome: Mechanism of Action, Role, and Therapeutics in Liver DiseasesSemantic proximity Read ↗

Cell type-specific roles of NLRP3, inflammasome-dependent and -independent, in host defense, sterile necroinflammation, tissue repair, and fibrosisSemantic proximity Read ↗

The inflammasome in liver diseaseSemantic proximity Read ↗

Hepatitis regulation by the inflammasome signaling pathwaySemantic proximity Read ↗

The Role of NLR-related Protein 3 Inflammasome in Host Defense and Inflammatory DiseasesSemantic proximity Read ↗

Inflammasomes and Their ActivationSemantic proximity Read ↗

Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice.Semantic proximity Read ↗

MicroRNA 223 3p Negatively Regulates the NLRP3 Inflammasome in Acute and Chronic Liver InjurySemantic proximity Read ↗

The Role of the NLRP3 Inflammasome in HCC Carcinogenesis and Treatment: Harnessing Innate ImmunitySemantic proximity Read ↗

Inflammasome activation: from inflammatory disease to infectionSemantic proximity Read ↗

Regulation of the NLRP3 Inflammasome by Post-Translational Modifications and Small MoleculesSemantic proximity Read ↗

Activation and Regulation of NLRP3 by Sterile and Infectious InsultsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.