Article
Cytosolic herpes simplex virus capsids not only require binding inner tegument protein pUL36 but also pUL37 for active transport prior to secondary envelopment.
Cellular microbiology - 1 Feb 2013
Sandbaumhüter Malte, Döhner Katinka, Schipke Julia, Binz Anne, Pohlmann Anja, Sodeik Beate, Bauerfeind Rudolf
Abstract excerpt
As the inner tegument proteins pUL36 and pUL37 of alphaherpesviruses may contribute to efficient intracellular transport of viral particles, we investigated their role in cytosolic capsid motility during assembly of herpes simplex virus type 1 (HSV1). As reported previously for pUL36, untagged pUL37 and UL37GFP bound to cytosolic capsids before these acquired outer tegument and envelope proteins. Capsids tagged...
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