Article
Genetic variant SLC2A2 [corrected] Is associated with risk of cardiovascular disease – assessing the individual and cumulative effect of 46 type 2 diabetes related genetic variants.
PloS one - 1 Jan 2012
Borglykke Anders, Grarup Niels, Sparsø Thomas, Linneberg Allan, Fenger Mogens, Jeppesen Jørgen, Hansen Torben, Pedersen Oluf, Jørgensen Torben
Abstract excerpt
AIM: To assess the individual and combined effect of 46 type 2 diabetes related risk alleles on incidence of a composite CVD endpoint. METHODS: Data from the first Danish MONICA study (N = 3523) and the Inter99 study (N = 6049) was used. Using Cox proportional hazard regression the individual effect of each risk allele on incident CVD was analyzed. Risk was presented as hazard ratios (HR) per risk allele....
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