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Article

Prokaryotic caspase homologs: phylogenetic patterns and functional characteristics reveal considerable diversity.

PloS one - 1 Jan 2012

Asplund-Samuelsson Johannes, Bergman Birgitta, Larsson John

Abstract excerpt

Caspases accomplish initiation and execution of apoptosis, a programmed cell death process specific to metazoans. The existence of prokaryotic caspase homologs, termed metacaspases, has been known for slightly more than a decade. Despite their potential connection to the evolution of programmed cell death in eukaryotes, the phylogenetic distribution and functions of these prokaryotic metacaspase sequences are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23185476
DOI: 10.1371/journal.pone.0049888
PMCID: PMC3501461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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