Multiple mechanisms in serum factor-induced resistance of Haemophilus influenzae type b to antibody.

doi:10.1128/iai.58.4.914-919.1990

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Article

Multiple mechanisms in serum factor-induced resistance of Haemophilus influenzae type b to antibody.

Infection and immunity - 1 Apr 1990

Kuratana M, Hansen E J, Anderson P

Abstract excerpt

Incubation of Haemophilus influenzae type b at less than or equal to 10(7) CFU/ml with serum ultrafiltrate induces a phenotypic conversion in which complement-mediated bactericidal activity by somatic antibodies decreases while killing by capsular antibody is unchanged. Conversion had been shown...

Topics

Antibodies, Bacterial
Blood Bactericidal Activity
Complement System Proteins
Haemophilus influenzae
Humans
Lipopolysaccharides
Neutrophils
Phagocytosis
Phenotype
Polysaccharides

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