Article
The extended survival of tw5/tw5 mouse embryo cells in vitro.
Genetical research - 1 Feb 1990
Garside W, Hillman N
Abstract excerpt
The tw5 haplotype is a recessive mutation which is lethal when homozygous in mouse embryos following implantation. This series of studies was undertaken to determine the effect of the tw5/tw5 genotype on embryos developing in vitro. Blastocyst embryos from +/tw5 inter se matings were compared with control blastocysts obtained from matings between T/+ and +/+ females and +/tw5 males for their abilities to continue...
Topics
- Animals
- Cell Survival
- Cells, Cultured
- Female
- Genes, Recessive
- Genotype
- Haplotypes
- Homozygote
- Male
- Mice
- Mice, Inbred BALB C
- Mutation