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Article

Localization of specificity determining sites in cadherin cell adhesion molecules.

Cell - 6 Apr 1990

Nose A, Tsuji K, Takeichi M

Abstract excerpt

Cadherins are a group of homophilic intercellular adhesion molecules; each member of this family exhibits binding specificity. Here, we attempted to map the sites for the specificities of these molecules by analyzing adhesives selectivities of the cells that express chimeric and point-mutated E- and P-cadherin. The results showed that the amino-terminal 113 amino acid region is essential to determine the...

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PMID: 2317870
DOI: 10.1016/0092-8674(90)90222-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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