Article
Localization of specificity determining sites in cadherin cell adhesion molecules.
Cell - 6 Apr 1990
Nose A, Tsuji K, Takeichi M
Abstract excerpt
Cadherins are a group of homophilic intercellular adhesion molecules; each member of this family exhibits binding specificity. Here, we attempted to map the sites for the specificities of these molecules by analyzing adhesives selectivities of the cells that express chimeric and point-mutated E-...
Topics
- Amino Acid Sequence
- Animals
- Binding Sites
- Cadherins
- Calcium
- Cell Aggregation
- Cell Membrane
- Chimera
- Humans
- L Cells
- Mice
- Molecular Sequence Data
- Mutation
- Sequence Homology, Nucleic Acid