Article
Association of endothelial nitric oxide synthase gene variants (-786 T>C, intron 4 b/a VNTR and 894 G>T) with idiopathic recurrent pregnancy loss: A case-control study with haplotype and in silico analysis.
European journal of obstetrics, gynecology, and reproductive biology - 1 Aug 2017
Azani Alireza, Hosseinzadeh Asghar, Azadkhah Roya, Zonouzi Ali Akbar Poursadegh, Zonouzi Ahmad Poursadegh, Aftabi Younes, Khani Hourieh, Heidary Leida, Danaii Shahla, Bargahi Nasrin, Pouladi Nasser, Hosseini Sayed Mostafa
Abstract excerpt
OBJECTIVE(S): Many lines of evidence suggest that reduced production of nitric oxide (NO) due to single nucleotide polymorphisms in endothelial nitric oxide synthase (eNOS) gene may affect the implantation and maintenance of pregnancy. Accordingly, our objective was to investigate whether the eNOS polymorphisms (-786 T>C, intron 4 b/a VNTR and 894 G>T) and haplotypes may be associated with increased...
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