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Article

Wnt6 Is Essential for Stromal Cell Proliferation During Decidualization in Mice1

23 Nov 2012

Abstract excerpt

Postimplantation uterine development involves extensive stromal cell proliferation and decidual transformation with polyploidization, which is essential for normal pregnancy establishment. However, it remains largely unknown how stromal proliferation versus decidual polyploidization is differentially regulated during decidualization. Utilizing Wnt6-mutant mice, we show here that Wnt6 deficiency impairs stromal...

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PMID: 23175771
DOI: 10.1095/biolreprod.112.104687

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