Article
A PCV2 vaccine based on genotype 2b is more effective than a 2a-based vaccine to protect against PCV2b or combined PCV2a/2b viremia in pigs with concurrent PCV2, PRRSV and PPV infection.
Vaccine - 7 Jan 2013
Opriessnig Tanja, O'Neill Kevin, Gerber Priscilla F, de Castro Alessandra M M G, Gimenéz-Lirola Luis G, Beach Nathan M, Zhou Lei, Meng Xiang-Jin, Wang Chong, Halbur Patrick G
Abstract excerpt
The predominant genotype of porcine circovirus (PCV) in the pig population today is PCV2b yet PCV2a-based commercial vaccines are considered effective in protecting against porcine circovirus associated disease. The objective of this study was to compare the ability of PCV2a- and PCV2b-based vaccines to control PCV2b viremia in a challenge model that mimics the U.S. field situation. Sixty-three pigs were randomly...
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