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Efficacy test of a plant-based porcine circovirus type 2 (PCV2) virus-like particle vaccine against four PCV2 genotypes (2a, 2b, 2d, and 2e) in pigs.

Veterinary microbiology - 1 Sept 2022

Oh Taehwan, Suh Jeongmin, Cho Hyejean, Min Kyungmin, Choi Bo-Hwa, Chae Chanhee

Abstract excerpt

The objective of this study was to evaluate the efficacy of a recombinant porcine circovirus type 2 (PCV2) vaccine based from a Nicotiana benthamiana expression system against four different co-challenges with PCV2 genotypes (2a, 2b, 2d, and 2e) and porcine reproductive and respiratory syndrome virus (PRRSV). Pigs in the vaccinated groups each received a 1.0 mL intramuscularly of plant-based PCV2a vaccine in the...

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PMID: 35853407
DOI: 10.1016/j.vetmic.2022.109512

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