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The role of <scp>AHI</scp>1 and <scp>CDKN</scp>1C in cutaneous <scp>T</scp>‐cell lymphoma progression

1 Oct 2012

Abstract excerpt

Cutaneous T-cell lymphoma (CTCL) is the most common lymphoma of the skin. Recent reports suggest that AHI1 is overexpressed in a subset of CTCL-derived cell lines, where it downregulates the expression of CDKN1C tumor suppressor gene. In the current work, we test the expression of these genes in 60 patients with Mycosis Fungoides and Sezary Syndrome by RT-PCR and correlate our findings with 6 years of clinical...

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PMID: 23171462
DOI: 10.1111/exd.12039

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