Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Local receptor revision and class switching to IgE in chronic rhinosinusitis with nasal polyps

15 Nov 2012

Abstract excerpt

BACKGROUND: Chronic rhinosinusitis with nasal polyps (NP) and allergic rhinitis (AR) is characterized by local Th2 inflammation and up-regulation of IgE; however, IgE in NP is 'polyclonal' and allergen specific, whereas IgE in AR is 'oligoclonal' and allergen specific. Germinal center (GC) reactions occur in AR, while only the formation of GC-like structures in NP is described. The aim of this study was to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allergic Rhinitis and Sensitization
Share to Asthma and respiratory diseases
Share to Sinusitis and nasal conditions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23157682
DOI: 10.1111/all.12054

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Local receptor revision and class switching to IgE in chronic rhinosinusitis with nasal polypsPMID 23157682Read ↗

Local increase in IgE and class switch recombination to IgE in nasal polyps in chronic rhinosinusitis.Semantic proximity Read ↗

Increased local IgE production induced by common aeroallergens and phenotypic alteration of mast cells in Chinese eosinophilic, but not non-eosinophilic, chronic rhinosinusitis with nasal polyps.Semantic proximity Read ↗

Local inflammation in chronic upper airway disease.Semantic proximity Read ↗

Chronic rhinosinusitis phenotypes.Semantic proximity Read ↗

Local Respiratory Allergy: From Rhinitis Phenotype to Disease Spectrum.Semantic proximity Read ↗

Non-allergic rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology.Semantic proximity Read ↗

Chronic rhinosinusitis and asthma: novel understanding of the role of IgE 'above atopy'.Semantic proximity Read ↗

Chronic rhinosinusitis: from one disease to different phenotypes.Semantic proximity Read ↗

SεSμ and SεSγ Switch Circles in Human Nasal Mucosa Following Ex Vivo Allergen Challenge: Evidence for Direct as Well as Sequential Class Switch RecombinationSemantic proximity Read ↗

MBP-positive and CD11c-positive cells are associated with different phenotypes of Korean patients with non-asthmatic chronic rhinosinusitis.Semantic proximity Read ↗

Single-cell analysis of human nasal mucosal IgE antibody secreting cells reveals a newly minted phenotype.Semantic proximity Read ↗

S100A8 Enhances IL-1β Production from Nasal Epithelial Cells in Eosinophilic Chronic RhinosinusitisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.