Article
Average locus differences in mutability related to protein "class": a hypothesis.
Proceedings of the National Academy of Sciences of the United States of America - 1 Mar 1990
Neel J V
Abstract excerpt
Substantially less genetic variation has been recognized in studies of the proteins of nucleated cells by the technique of two-dimensional polyacrylamide gel electrophoresis than has been encountered in studies of serum transport proteins and erythrocyte enzymes with one-dimensional electrophoresis. Technical factors appear to account for only part of the difference. The two remaining (nonexclusive) explanations...
Topics
- Biological Evolution
- Electrophoresis, Gel, Two-Dimensional
- Electrophoresis, Polyacrylamide Gel
- Heterozygote
- Humans
- Models, Genetic
- Mutation
- Proteins