Article
Induction of competence for natural transformation in Legionella pneumophila and exploitation for mutant construction.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013
Buchrieser Carmen, Charpentier Xavier
Abstract excerpt
Many Gram-positive and Gram-negative bacteria possess natural competence mechanisms for DNA -capture and internalization that play an important role in diversifying adaptation of bacteria through horizontal gene transfer. Natural transformation and other mechanisms of horizontal gene transfer are dependent on DNA recombination. Natural competence can be exploited both for studying adaptation and horizontal gene...
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