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Article

Impact of Ischemia and Procurement Conditions on Gene Expression in Renal Cell Carcinoma

8 Nov 2012

Abstract excerpt

PURPOSE: Previous studies have shown that ischemia alters gene expression in normal and malignant tissues. There are no studies that evaluated effects of ischemia in renal tumors. This study examines the impact of ischemia and tissue procurement conditions on RNA integrity and gene expression in renal cell carcinoma. EXPERIMENTAL DESIGN: Ten renal tumors were resected without renal hilar clamping from 10 patients...

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PMID: 23136194
DOI: 10.1158/1078-0432.ccr-12-2606

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