Gene expression in colorectal neoplasia: modifications induced by tissue ischaemic time and tissue handling protocol

Abstract excerpt

AIMS: The heterogeneity within individual distinct cancer types in terms of behaviour, response to therapy and prognosis is well recognized. A major goal of translational research projects has therefore been to define clinically significant subgroups of individual tumour types by analysis of mRNA as well as protein expression. An essential premise of such investigations is that expression of these key molecules...

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