Article
Genomic comparison of Escherichia coli O104:H4 isolates from 2009 and 2011 reveals plasmid, and prophage heterogeneity, including shiga toxin encoding phage stx2.
PloS one - 1 Jan 2012
Ahmed Sanaa A, Awosika Joy, Baldwin Carson, Bishop-Lilly Kimberly A, Biswas Biswajit, Broomall Stacey, Chain Patrick S G, Chertkov Olga, Chokoshvili Otar, Coyne Susan, Davenport Karen, Detter J Chris, Dorman William, Erkkila Tracy H, Folster Jason P, Frey Kenneth G, George Matroner, Gleasner Cheryl, Henry Matthew, Hill Karen K, Hubbard Kyle, Insalaco Joseph, Johnson Shannon, Kitzmiller Aaron, Krepps Michael, Lo Chien-Chi, Luu Truong, McNew Lauren A, Minogue Timothy, Munk Christine A, Osborne Brian, Patel Mohit, Reitenga Krista G, Rosenzweig C Nicole, Shea April, Shen Xiaohong, Strockbine Nancy, Tarr Cheryl, Teshima Hazuki, van Gieson Eric, Verratti Kathleen, Wolcott Mark, Xie Gary, Sozhamannan Shanmuga, Gibbons Henry S
Abstract excerpt
In May of 2011, an enteroaggregative Escherichia coli O104:H4 strain that had acquired a Shiga toxin 2-converting phage caused a large outbreak of bloody diarrhea in Europe which was notable for its high prevalence of hemolytic uremic syndrome cases. Several studies have described the genomic inventory and phylogenies of strains associated with the outbreak and a collection of historical E. coli O104:H4 isolates...
Topics
- Area Under Curve
- DNA
- Disease Outbreaks
- Escherichia coli
- Escherichia coli Infections