Article
Comparative genomic analysis of two novel sporadic Shiga toxin-producing Escherichia coli O104:H4 strains isolated 2011 in Germany.
PloS one - 1 Jan 2015
Tietze Erhard, Dabrowski Piotr Wojciech, Prager Rita, Radonic Aleksandar, Fruth Angelika, Auraß Philipp, Nitsche Andreas, Mielke Martin, Flieger Antje
Abstract excerpt
A large outbreak of gastrointestinal disease occurred in 2011 in Germany which resulted in almost 4000 patients with acute gastroenteritis or hemorrhagic colitis, 855 cases of a hemolytic uremic syndrome and 53 deaths. The pathogen was an uncommon, multiresistant Escherichia coli strain of serotype O104:H4 which expressed a Shiga toxin characteristic of enterohemorrhagic E. coli and in addition virulence factors...
Topics
- Animals
- Bacterial Adhesion
- Chlorocebus aethiops
- DNA, Bacterial
- Disease Outbreaks
- Escherichia coli Infections
- Genome, Bacterial
- Germany
- Hep G2 Cells
- Humans
- Molecular Sequence Data
- Phylogeny
- Plasmids