Article
Sequence variants in eukaryotic translation initiation factor 4-gamma (eIF4G1) are associated with Lewy body dementia.
Acta neuropathologica - 1 Mar 2013
Fujioka Shinsuke, Sundal Christina, Strongosky Audrey J, Castanedes Monica Case, Rademakers Rosa, Ross Owen A, Vilariño-Güell Carles, Farrer Matthew J, Wszolek Zbigniew K, Dickson Dennis W
Abstract excerpt
We recently reported a missense mutation and four variants in eukaryotic translation initiation factor 4-gamma (EIF4G1) associated with parkinsonism, dementia or both. In those with a positive family history, the mode of inheritance was autosomal dominant. Detailed neuropathologic descriptions of individuals with EIF4G1 genetic variants have not been reported. Herein, we report neuropathologic findings of three...
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