Article
Role of polyadenylation in regulation of the flagella cascade and motility in Escherichia coli.
Biochimie - 1 Feb 2013
Maes Alexandre, Gracia Céline, Bréchemier Dominique, Hamman Philippe, Chatre Elodie, Lemelle Laurence, Bertin Philippe N, Hajnsdorf Eliane
Abstract excerpt
Polyadenylation is recognized as part of a surveillance machinery for eliminating defective RNA molecules in eukaryotes and prokaryotes. Escherichia coli strains, deficient in poly(A)polymerase I (PAP I), expressed less flagellin compared to wild-type strains. Because flagellin synthesis is a late step in the flagellar biosynthesis pathway, we assessed the role of PAP I in this cascade and in flagella function....
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