Article
Expression of histocompatibility antigens and characterization of the lymphocyte infiltrate in hyperplastic polyps of the large bowel.
Human pathology - 1 Mar 1990
Bedossa P, Poynard T, Bacci J, Naveau S, Lemaigre G, Chaput J C, Martin E
Abstract excerpt
HLA-DR expression, lymphocyte subsets, and the distribution of proliferating cells were studied in hyperplastic polyps from the colorectum. The density of T-cells (CD5+) (mean of cells/mm2 of tissue +/- SEM) was higher in the lamina propria of hyperplastic polyps (64.2 +/- 4.2) than in normal colonic mucosa (36.7 +/- 2.6, P less than .001). The CD4/CD8 ratio was higher in hyperplastic polyps (6.3 +/- 0.9, P less...
Topics
- Adenoma
- Aged
- Antigens, Surface
- Cell Division
- Colonic Neoplasms
- Epithelium
- HLA Antigens
- HLA-DR Antigens
- Humans
- Hyperplasia
- Intestinal Mucosa