Article
Known glioma risk loci are associated with glioma with a family history of brain tumours -- a case-control gene association study.
International journal of cancer - 15 May 2013
Melin Beatrice, Dahlin Anna M, Andersson Ulrika, Wang Zhaoming, Henriksson Roger, Hallmans Göran, Bondy Melissa L, Johansen Christoffer, Feychting Maria, Ahlbom Anders, Kitahara Cari M, Wang Sophia S, Ruder Avima M, Carreón Tania, Butler Mary Ann, Inskip Peter D, Purdue Mark, Hsing Ann W, Mechanic Leah, Gillanders Elizabeth, Yeager Meredith, Linet Martha, Chanock Stephen J, Hartge Patricia, Rajaraman Preetha
Abstract excerpt
Familial cancer can be used to leverage genetic association studies. Recent genome-wide association studies have reported independent associations between seven single nucleotide polymorphisms (SNPs) and risk of glioma. The aim of this study was to investigate whether glioma cases with a positive family history of brain tumours, defined as having at least one first- or second-degree relative with a history of...
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