Article
Complete nucleotide sequences of blaKPC-4- and blaKPC-5-harboring IncN and IncX plasmids from Klebsiella pneumoniae strains isolated in New Jersey.
Antimicrobial agents and chemotherapy - 1 Jan 2013
Chen Liang, Chavda Kalyan D, Fraimow Henry S, Mediavilla José R, Melano Roberto G, Jacobs Michael R, Bonomo Robert A, Kreiswirth Barry N
Abstract excerpt
Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae have emerged as major nosocomial pathogens. bla(KPC), commonly located on Tn4401, is found in Gram-negative bacterial strains, with the two most common variants, bla(KPC-2) and bla(KPC-3), identified in plasmids with diverse genetic backgrounds. In this study, we examined bla(KPC-4)- and bla(KPC-5)-bearing plasmids recovered from two K....
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