Article
Effects of route of inoculation and viral genetic variation on antibody responses to polyomavirus SV40 in Syrian golden hamsters.
Comparative medicine - 1 Oct 2012
Swain Jody L, Sroller Vojtech, Wong Connie, Zhang Shaojie, Halvorson Steven J, Herron Alan J, Kozinetz Claudia A, Butel Janet S
Abstract excerpt
Genetic variants of polyomavirus SV40 are powerful agents with which to define viral effects on cells and carcinogenesis pathways. We hypothesized that differences in biologic variation among viral strains affect the process of viral infection and are reflected in antibody responses to the viral nonstructural large T-antigen (TAg) protein but not in neutralizing antibody responses against the inoculated viral...
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