Article
Unraveling the genetics of common epilepsies: approaches, platforms, and caveats.
Epilepsy & behavior : E&B - 1 Mar 2013
Petrovski Slavé, Kwan Patrick
Abstract excerpt
With no known intervention to prevent or cure epilepsy, treatment is primarily symptomatic and requires long-term administration of medications to suppress seizure occurrence. Current antiepileptic drugs (AEDs) are ineffective in one-third of patients (Kwan and Brodie, 2000). Such therapeutic inadequacy is largely due to our insufficient understanding of the basic molecular pathophysiological processes that...
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