Efficacy of genotypic resistance-guided sequential therapy in the third-line treatment of refractory Helicobacter pylori infection: a multicentre clinical trial.

doi:10.1093/jac/dks407

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Article

Efficacy of genotypic resistance-guided sequential therapy in the third-line treatment of refractory Helicobacter pylori infection: a multicentre clinical trial.

The Journal of antimicrobial chemotherapy - 1 Feb 2013

Liou Jyh-Ming, Chen Chieh-Chang, Chang Chi-Yang, Chen Mei-Jyh, Fang Yu-Jen, Lee Ji-Yuh, Chen Chien-Chuan, Hsu Shih-Jer, Hsu Yao-Chun, Tseng Cheng-Hao, Tseng Ping-Huei, Chang Lawrence, Chang Wen-Hsiung, Wang Hsiu-Po, Shun Chia-Tung, Wu Jeng-Yih, Lee Yi-Chia, Lin Jaw-Town, Wu Ming-Shiang

Abstract excerpt

OBJECTIVES: The efficacy of sequential therapy and the applicability of genotypic resistance to guide the selection of antibiotics in the third-line treatment of Helicobacter pylori have not been reported. We aimed to assess the efficacy of genotypic resistance-guided sequential therapy in third-line treatment. METHODS: Genotypic and phenotypic resistances were determined in patients who failed at least two...

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PMID: 23099849
DOI: 10.1093/jac/dks407

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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