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Article

Efficacies of Genotypic Resistance-Guided vs Empirical Therapy for Refractory Helicobacter pylori Infection.

Gastroenterology - 1 Oct 2018

Liou Jyh-Ming, Chen Po-Yueh, Luo Jiing-Chyuan, Lee Ji-Yuh, Chen Chieh-Chang, Fang Yu-Jen, Yang Tsung-Hua, Chang Chi-Yang, Bair Ming-Jong, Chen Mei-Jyh, Hsu Yao-Chun, Hsu Wen-Feng, Chang Chun-Chao, Lin Jaw-Town, Shun Chia-Tung, El-Omar Emad M, Wu Ming-Shiang

Abstract excerpt

BACKGROUND & AIMS: We aimed to compare the efficacy of genotypic resistance-guided therapy vs empirical therapy for eradication of refractory Helicobacter pylori infection in randomized controlled trials. METHODS: We performed 2 multicenter, open-label trials of patients with H pylori infection (20 years or older) failed by 2 or more previous treatment regimens, from October 2012 through September 2017 in Taiwan....

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PMID: 29964036
DOI: 10.1053/j.gastro.2018.06.047

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