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Article

A modified maximum contrast method for unequal sample sizes in pharmacogenomic studies.

Statistical applications in genetics and molecular biology - 7 Sept 2011

Nagashima Kengo, Sato Yasunori, Hamada Chikuma

Abstract excerpt

In pharmacogenomic studies, biomedical researchers commonly analyze the association between genotype and biological response by using the Kruskal-Wallis test or one-way analysis of variance (ANOVA) after logarithmic transformation of the obtained data. However, because these methods detect unexpected biological response patterns, the power for detecting the expected pattern is reduced. Previously, we proposed a...

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PMID: 23089824
DOI: 10.2202/1544-6115.1560

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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