Article
The Neurospora crassa chr-1 gene is up-regulated by chromate and its encoded CHR-1 protein causes chromate sensitivity and chromium accumulation.
Current genetics - 1 Dec 2012
Flores-Alvarez Luis J, Corrales-Escobosa Alma R, Cortés-Penagos Carlos, Martínez-Pacheco Mauro, Wrobel-Zasada Kazimierz, Wrobel-Kaczmarczyk Katarzyna, Cervantes Carlos, Gutiérrez-Corona Félix
Abstract excerpt
The ChrA membrane protein belongs to the CHR superfamily of chromate ion transporters, which includes homologues from bacteria, archaea and eukaryotes. Bacterial ChrA homologues confer chromate resistance by exporting chromate ions from the cell's cytoplasm. The Neurospora crassa strain 74-A chr-1 gene encodes a putative CHR-1 protein of 507 amino acid residues, which belongs to the CHR superfamily. RT-PCR assays...
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