Article
[Clopidogrel resistance--risk factor in patients with acute coronary syndromes].
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi - 1 Jan 2000
Costache Irina luliana, Rusu Cristina, Ivanov I, Popescu Roxana, Petriş A
Abstract excerpt
Clopidogrel is an ADP receptor antagonist, an inhibitor of platelet activation and aggregation. The effect is due to its selective and irreversible blockade of the P2Y12 receptor. The concept of clopidogrel resistance emerged since several years ago. This biological finding has a very important impact especially in patients with acute coronary syndromes, explaining by this their worse evolution. Mechanisms of...
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