Article
Autosomal Dominant Transmission of Autoantibodies to Thyroglobulin and Thyroid Peroxidase*
1 Mar 1990
Abstract excerpt
The inheritance of autoantibodies to thyroglobulin and thyroid peroxidase (thyroid microsomal antigen) has been reevaluated with newly developed ultrasensitive assays that depend on the direct interaction between antibody and radiolabeled antigen. In a study of 16 families with autoimmune thyroid disease, autoantibodies to thyroid peroxidase (TPO) were found to be inherited as a dominant Mendelian trait in...
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