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Article

ETS variant 1 regulates matrix metalloproteinase-7 transcription in LNCaP prostate cancer cells

16 Oct 2012

Abstract excerpt

Prostate cancer is characterized by the recurrent translocation of ETS transcription factors, including ETS variant 1 (ETV1) [also known as ETS-related 81 (ER81)]. Transgenic ETV1 mice develop prostatic intraepithelial neoplasia, yet the mechanisms by which ETV1 exerts its deleterious function remain largely unexplored. In this study, we demonstrated that ETV1 is capable of binding to the matrix...

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PMID: 23076342
DOI: 10.3892/or.2012.2079

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