Emergence of HA mutants during influenza virus pneumonia.

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Article

Emergence of HA mutants during influenza virus pneumonia.

International journal of clinical and experimental pathology - 1 Jan 2012

Manríquez Maria Eugenia Vázquez, Makino Akiko, Tanaka Motoko, Abe Yasuhisa, Yoshida Hiroyuki, Morioka Ichiro, Arakawa Soichi, Takeshima Yasuhiro, Iwata Kentaro, Takasaki Jin, Manabe Toshie, Nakaya Takaaki, Nakamura Shota, Iglesias Anjarath Lorena Higuera, Rossales Rosa Maria Rivera, Mirabal Erika Pena, Ito Tateki, Kitazawa Toshio, Oka Teruaki, Yamashita Makoto, Kudo Koichiro, Shinya Kyoko

Abstract excerpt

During the influenza pandemic of 2009, the number of viral pneumonia cases showed a marked increase in comparison with seasonal influenza viruses. Mutations at amino acid 222 (D222G mutations) in the virus hemagglutinin (HA) molecule, known to alter the receptor-recognition properties of the virus, were detected in a number of the more severely-affected patients in the early phases of the pandemic. To understand...

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PMID: 23071861
PMCID: PMC3466977

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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