Article
Development of bioluminescent bioreporters for in vitro and in vivo tracking of Yersinia pestis.
PloS one - 1 Jan 2012
Sun Yanwen, Connor Michael G, Pennington Jarrod M, Lawrenz Matthew B
Abstract excerpt
Yersinia pestis causes an acute infection known as the plague. Conventional techniques to enumerate Y. pestis can be labor intensive and do not lend themselves to high throughput assays. In contrast, bioluminescent bioreporters produce light that can be detected using plate readers or optical imaging platforms to monitor bacterial populations as a function of luminescence. Here, we describe the development of two...
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