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Article

Multifactorial patterns of gene expression in colonic epithelial cells predict disease phenotypes in experimental colitis.

Inflammatory bowel diseases - 1 Nov 2012

Frantz Aubrey L, Bruno Maria E C, Rogier Eric W, Tuna Halide, Cohen Donald A, Bondada Subbarao, Chelvarajan R Lakshman, Brandon J Anthony, Jennings C Darrell, Kaetzel Charlotte S

Abstract excerpt

BACKGROUND: The pathogenesis of inflammatory bowel disease (IBD) is complex and the need to identify molecular biomarkers is critical. Epithelial cells play a central role in maintaining intestinal homeostasis. We previously identified five "signature" biomarkers in colonic epithelial cells (CEC) that are predictive of disease phenotype in Crohn's disease. Here we investigate the ability of CEC biomarkers to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23070952
DOI: 10.1002/ibd.22923
PMCID: PMC3476470

Genes

MIP
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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