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Article

In vivo 17β-estradiol treatment contributes to podocyte actin stabilization in female db/db mice.

Endocrinology - 1 Dec 2012

Catanuto Paola, Fornoni Alessia, Pereira-Simon Simone, Wu Fayi, Burnstein Kerry L, Xia Xiaomei, Conti Francesco, Lenzi Andrea, Elliot Sharon

Abstract excerpt

We recently showed that 17β-estradiol (E(2)) treatment ameliorated type 2 diabetic glomerulosclerosis in mice in part by protecting podocyte structure and function. Progressive podocyte damage is characterized by foot process effacement, vacuolization, detachment of podocytes from the glomerular...

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Identifiers

PMID: 23070549
DOI: 10.1210/en.2012-1637
PMCID: PMC3512061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23070549-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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