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Article

Identification of novel HLA class II target epitopes for generation of donor-specific T regulatory cells.

Clinical immunology (Orlando, Fla.) - 1 Nov 2012

Stone Brad, Rieck Mary, Rawlings Crystal A, Kas Arnold, Shendure Jay, Jones Hywel, Buckner Jane H

Abstract excerpt

Therapies capable of generating host T regulatory cells (T(R)) responsive to donor-specific HLA-class II minor histocompatibility antigens have the potential to promote tolerance of a transplanted organ. Our group has developed a novel approach for the identification of potentially therapeutic T(R) target antigens. We perform parallel non-synonymous SNP genotyping of HLA-identical subject pairs to identify...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23063892
DOI: 10.1016/j.clim.2012.09.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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